2 Rheumatoid Arthritis Medication Tied to Decrease Danger of Parkinson’s

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News Picture: 2 Rheumatoid Arthritis Drugs Tied to Lower Risk of Parkinson's

FRIDAY, Jan. 28, 2022 (HealthDay Information)

Two rheumatoid arthritis drugs present potential for reducing the danger of Parkinson’s illness, new analysis reveals.

Some earlier research have discovered that folks with rheumatoid arthritis have a decrease danger of Parkinson’s, and it was recommended {that a} class of rheumatoid arthritis drugs referred to as disease-modifying antirheumatic medication (DMARDs) might play a task in that diminished danger.

To study extra, researchers analyzed information from hundreds of sufferers in Finland.

Using most DMARDs — together with methotrexate, sulfasalazine, gold preparations or immunosuppressants — a minimum of three years earlier than Parkinson’s illness analysis was not related to the danger of the illness in these with rheumatoid arthritis, in keeping with the examine printed on-line Jan. 21 within the journal Neurology.

Nonetheless, the researchers did discover that rheumatoid arthritis sufferers who took the DMARDs chloroquine or hydroxychloroquine had a 26% decrease danger of Parkinson’s illness.

Each of those medication have an effect on the immune system and have been proven to have anti-Parkinson’s potential in animal research, in keeping with the researchers. However outcomes of animal research are sometimes totally different from these in people.

The new study was led by Anne Paakinaho of the College of Pharmacy on the College of Jap Finland in Kuopio.

Her group referred to as for additional investigation of the medication’ potential protecting results towards Parkinson’s.

The examine — funded by the Michael J. Fox Foundation for Parkinson’s Research — managed for size of time with rheumatoid arthritis, age, intercourse and different well being circumstances, corresponding to heart disease and diabetes.

The danger components for Parkinson’s illness are unclear, the examine authors famous in a journal information launch.

Earlier research have linked rheumatoid arthritis with Parkinson’s. However they’ve yielded conflicting findings, with rheumatoid arthritis being related to both a decrease or greater danger of Parkinson’s.

Extra data

The Parkinson’s Basis has extra on Parkinson’s disease.

SOURCE: College of Jap Finland, information launch, Jan. 24, 2022

Robert Preidt

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